Proposed MedDRA Version 22.0 Complex Changes - Reminder

4 September 2018

The MSSO has posted proposed complex changes for MedDRA Version 22.0 on  the MedDRA website in the Change Request section under “Related Documents.” Complex changes are changes to the MedDRA hierarchy, i.e., the High Level Terms (HLTs), High Level Group Terms (HLGTs), or System Organ Classes (SOCs).

We encourage your comments both for and against the proposed complex changes so that we can understand the potential impact on your use of MedDRA.

The deadline for your response to these proposals is 21 September 2018.  Please send your comments to